Engineering large animal models of human disease
نویسندگان
چکیده
منابع مشابه
Engineering large animal models of human disease
The recent development of gene editing tools and methodology for use in livestock enables the production of new animal disease models. These tools facilitate site-specific mutation of the genome, allowing animals carrying known human disease mutations to be produced. In this review, we describe the various gene editing tools and how they can be used for a range of large animal models of disease...
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ژورنال
عنوان ژورنال: The Journal of Pathology
سال: 2015
ISSN: 0022-3417,1096-9896
DOI: 10.1002/path.4648